Zepbound (tirzepatide) 7.5 mg/0.5 mL – Key Details
Zepbound 7.5 mg/0.5 mL is the third dose in the titration schedule for chronic weight management. It is typically prescribed after 4 weeks each on 2.5 mg (starter dose) and 5 mg (initial therapeutic dose).
🔹 Dosage & Administration
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Strength: 7.5 mg per 0.5 mL injection.
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Frequency: Once weekly (subcutaneous, same day each week).
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Pen Type: Single-use, pre-filled auto-injector.
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Titration Schedule:
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Weeks 1–4: 2.5 mg
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Weeks 5–8: 5 mg
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Weeks 9+: 7.5 mg (may increase further if needed)
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Note: Some patients stay on 7.5 mg if they achieve sufficient weight loss, while others continue to higher doses (10 mg → 12.5 mg → 15 mg).
🔹 Effectiveness for Weight Loss
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In clinical trials, patients on tirzepatide 7.5 mg lost an average of ~15–18% of body weight over 72 weeks (with diet/exercise).
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Higher doses (10–15 mg) may lead to 20%+ weight loss but can increase side effects.
🔹 Common Side Effects
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Most frequent: Nausea, diarrhea, constipation, vomiting, indigestion.
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Less common: Fatigue, dizziness, mild hypoglycemia (if taking diabetes meds).
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Serious (rare): Pancreatitis, gallbladder issues, kidney injury, allergic reactions.
💡 Tip: Side effects often lessen over time. Staying hydrated and eating smaller, low-fat meals can help.
🔹 Storage & Handling
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Before first use: Refrigerate (2–8°C / 36–46°F).
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After first use: Can be kept at room temp (≤30°C / 86°F) for up to 21 days.
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Do NOT freeze or expose to direct heat/light.
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